Rigid Motion Invariant Statistical Shape Modeling based on Discrete Fundamental Forms
We present a novel approach for nonlinear statistical shape modeling that is
invariant under Euclidean motion and thus alignment-free. By analyzing metric
distortion and curvature of shapes as elements of Lie groups in a consistent
Riemannian setting, we construct a framework that reliably handles large
deformations. Due to the explicit character of Lie group operations, our
non-Euclidean method is very efficient allowing for fast and numerically robust
processing. This facilitates Riemannian analysis of large shape populations
accessible through longitudinal and multi-site imaging studies providing
increased statistical power. Additionally, as planar configurations form a
submanifold in shape space, our representation allows for effective estimation
of quasi-isometric surfaces flattenings. We evaluate the performance of our
model w.r.t. shape-based classification of hippocampus and femur malformations
due to Alzheimer's disease and osteoarthritis, respectively. In particular, we
outperform state-of-the-art classifiers based on geometric deep learning as
well as statistical shape modeling especially in presence of sparse training
data. We evaluate the performance of our model w.r.t. shape-based
classification of pathological malformations of the human knee and show that it
outperforms the standard Euclidean as well as a recent nonlinear approach
especially in presence of sparse training data. To provide insight into the
model's ability of capturing biological shape variability, we carry out an
analysis of specificity and generalization ability.
Authors
Felix Ambellan, Stefan Zachow, Christoph von Tycowicz